Article
Prevalence of drug resistance-conferring mutations associated with isoniazid- and rifampicin-resistant Mycobacterium tuberculosis in Ethiopia: a systematic review and meta-analysis.
Journal of global antimicrobial resistance - 1 Sept 2021
Reta Melese Abate, Alemnew Birhan, Abate Biruk Beletew, Fourie P Bernard
Abstract excerpt
OBJECTIVES: Globally, the incidence and mortality of tuberculosis (TB) are declining; however, low detection of drug-resistant disease threatens to reverse current progress toward global TB control. Multiple rapid molecular diagnostic tests have recently been developed to detect genetic mutations in Mycobacterium tuberculosis (Mtb) known to confer drug resistance. However, their utility depends on the frequency...
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