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Article

Bmp4 from the optic vesicle specifies murine retina formation.

Developmental biology - 1 Jun 2015

Huang Jie, Liu Ying, Oltean Alina, Beebe David C

Abstract excerpt

Previous studies of mouse embryos concluded that after the optic vesicle evaginates from the ventral forebrain and contacts the surface ectoderm, signals from the ectoderm specify the distal region of the optic vesicle to become retina and signals from the optic vesicle induce the lens. Germline deletion of Bmp4 resulted in failure of lens formation. We performed conditional deletion of Bmp4 from the optic...

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Bone Morphogenetic Protein 4
Chick Embryo
Eye
Gene Expression Regulation, Developmental
In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lens, Crystalline

Retinal Pigment Epithelium

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Identifiers

PMID: 25792196
DOI: 10.1016/j.ydbio.2015.03.006
PMCID: PMC4523094

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Bmp4 from the optic vesicle specifies murine retina formation.PMID 25792196Read ↗

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