Article
Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish.
Developmental biology - 1 Nov 2012
Kruse-Bend Renee, Rosenthal Jude, Quist Tyler S, Veien Eric S, Fuhrmann Sabine, Dorsky Richard I, Chien Chi-Bin
Abstract excerpt
Dorsal retinal fate is established early in eye development, via expression of spatially restricted dorsal-specific transcription factors in the optic vesicle; yet the events leading to initiation of dorsal fate are not clear. We hypothesized that induction of dorsal fate would require an extraocular signal arising from a neighboring tissue to pattern the prospective dorsal retina, however no such signal has been...
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