Article
The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo.
Developmental biology - 15 Mar 2003
Collinson J Martin, Quinn Jane C, Hill Robert E, West John D
Abstract excerpt
The roles of Pax6 were investigated in the murine eye and the olfactory epithelium by analysing gene expression and distribution of Pax6(-/-) cells in Pax6(+/+) <--> Pax6(-/-) chimeras. It was found that between embryonic days E10.5 and E16.5 Pax6 is autonomously required for cells to contribute fully not only to the corneal epithelium, where Pax6 is expressed at high levels, but also to the to the corneal stroma...
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