Article
Polymorphisms in Plasmodium falciparum K13-propeller in Angola and Mozambique after the introduction of the ACTs.
PloS one - 1 Jan 2015
Escobar Carlos, Pateira Sara, Lobo Elsa, Lobo Lis, Teodosio Rosa, Dias Fernanda, Fernandes Natercia, Arez Ana Paula, Varandas Luis, Nogueira Fatima
Abstract excerpt
We report the presence of SNPs in Plasmodium falciparum K13-propeller gene in two African countries, Angola and Mozambique, where malaria is a serious public health problem. Samples were collected before and after ACT introduction as first-line treatment. In each country 50 samples collected before and 50 after ACT introduction were analysed. A total of three different mutations (R471R and R575R in Angola and...
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