Article
Uric acid and cardiovascular risk: What genes can say.
International journal of clinical practice - 1 Jan 2018
Kei Anastazia, Koutsouka Freideriki, Makri Andromachi, Elisaf Moses
Abstract excerpt
BACKGROUND: Although the relationship of elevated serum uric acid levels and cardiovascular disease has been established in a great number of studies, the causal relevance of this finding remains ambiguous. An approach to evaluate the causal relevance of biomarkers is to exploit the natural randomised allocation of allelic variation in genes affecting their level, also known as Mendelian randomisation. AIM: The...
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