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Article

Alteration of the Centromedial Amygdala Glutamatergic Synapses by the BDNF Val66Met Polymorphism.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2015

Galvin Christopher, Lee Francis S, Ninan Ipe

Abstract excerpt

Fear expression is mediated by an activation of the centromedial amygdala (CEm), the major output nucleus of the amygdaloid complex. Consistently, fear extinction is associated with an increased synaptic inhibition as well as a suppression of the excitability of the CEm neurons. However, little is known about the role of CEm glutamatergic synapses in fear regulation and anxiety-like behaviors. The BDNF Val66Met,...

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Source

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Identifiers

PMID: 25786582
DOI: 10.1038/npp.2015.76
PMCID: PMC4613621

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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