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Article

Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism.

Behavioral neuroscience - 1 Feb 2010

Lonsdorf Tina B, Weike Almut I, Golkar Armita, Schalling Martin, Hamm Alfons O, Öhman Arne

Abstract excerpt

The brain-derived neurotrophic factor (BDNF) is critically involved in neuroplasticity, as well as the acquisition, consolidation, and retention of hippocampal- and amygdala-dependent learning. A common functional A-->G single nucleotide polymorphism (BDNFval66met) in the prodomain of the human BDNF gene is associated with abnormal intracellular trafficking and reduced activity-dependent BDNF release. We studied...

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Identifiers

PMID: 20141276
DOI: 10.1037/a0018261
PMCID: PMC2862474

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism.PMID 20141276Read ↗

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