Article
A common human brain-derived neurotrophic factor polymorphism leads to sustained depression of excitatory synaptic transmission by isoflurane in hippocampus
2022-01-01
Abstract excerpt
Multiple presynaptic and postsynaptic targets have been identified for the reversible neurophysiological effects of general anesthetics on synaptic transmission and neuronal excitability. However, the synaptic mechanisms involved in persistent depression of synaptic transmission resulting in more prolonged neurological dysfunction following anesthesia are less clear. Here, we show that brain-derived neurotrophic f...
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Identifiers and source
- Literature Corpus work
- 004167d3-be34-56a1-8535-20f12bdd9d3c
- DOI
- 10.1101/2021.12.30.474566