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Article

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder.

Trends in neurosciences - 1 Jan 2012

Mahan Amy L, Ressler Kerry J

Abstract excerpt

Posttraumatic stress disorder (PTSD) is an anxiety disorder that can develop after a traumatic experience such as domestic violence, natural disasters or combat-related trauma. The cost of such disorders on society and the individual can be tremendous. In this article, we review how the neural circuitry implicated in PTSD in humans is related to the neural circuitry of fear. We then discuss how fear conditioning...

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Identifiers

PMID: 21798604
DOI: 10.1016/j.tins.2011.06.007
PMCID: PMC3206195

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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