Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder.

Trends in neurosciences - 1 Jan 2012

Mahan Amy L, Ressler Kerry J

Abstract excerpt

Posttraumatic stress disorder (PTSD) is an anxiety disorder that can develop after a traumatic experience such as domestic violence, natural disasters or combat-related trauma. The cost of such disorders on society and the individual can be tremendous. In this article, we review how the neural ci...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amygdala
Share to Brain
Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conditioning, Psychological

Share to Neuronal Plasticity

Share to Signal Transduction

Share to Stress Disorders, Post-Traumatic

Source

Open in PubMed Open full text

Identifiers

PMID: 21798604
DOI: 10.1016/j.tins.2011.06.007
PMCID: PMC3206195

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21798604-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder.PMID 21798604Read ↗

Pavlovian fear memory circuits and phenotype models of PTSD.Semantic proximity Read ↗

How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD.Semantic proximity Read ↗

Stress, trauma and PTSD: translational insights into the core synaptic circuitry and its modulation.Semantic proximity Read ↗

Towards new approaches to disorders of fear and anxiety.Semantic proximity Read ↗

Interaction of Brain-derived Neurotrophic Factor, Exercise, and Fear Extinction: Implications for Post-traumatic Stress Disorder.Semantic proximity Read ↗

PTSD and gene variants: new pathways and new thinking.Semantic proximity Read ↗

A formal model of anxiety disorders based on the neural circuit dynamics of the fear and extinction circuitsSemantic proximity Read ↗

The BDNF Val66Met polymorphism moderates the relationship between Posttraumatic Stress Disorder and fear extinction learning.Semantic proximity Read ↗

Dynamic Patterns of Threat-Associated Gene Expression in the Amygdala and BloodSemantic proximity Read ↗

Easy to remember, difficult to forget: the development of fear regulation.Semantic proximity Read ↗

Integrating Threat Conditioning and the Hierarchical Taxonomy of Psychopathology (HiTOP) to Advance the Study of Anxiety-Related PsychopathologySemantic proximity Read ↗

Investigational drugs under development for the treatment of PTSD.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.