Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex differences in skeletal muscle phosphatase and tensin homolog deleted on chromosome 10 (PTEN) levels: a cross-sectional study.

Scientific reports - 17 Mar 2015

Samaan M Constantine, Anand Sonia S, Sharma Arya M, Samjoo Imtiaz A, Tarnopolsky Mark A

Abstract excerpt

Women have higher adiposity but maintain insulin sensitivity when compared to men. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibits insulin signaling, but it is not known if PTEN regulate insulin resistance in a sex-specific manner. In this cross-sectional study, muscle biopsies from participants in the Molecular Study of Health and Risk in Ethnic Groups (Mol-SHARE) were used to test for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Glyceraldehyde-3-Phosphate Dehydrogenases

Share to Muscle, Skeletal

Share to Organ Size

Share to PTEN Phosphohydrolase

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25777795
DOI: 10.1038/srep09154
PMCID: PMC4366049

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex differences in skeletal muscle phosphatase and tensin homolog deleted on chromosome 10 (PTEN) levels: a cross-sectional study.PMID 25777795Read ↗

The association of PTEN/PI3K/Akt pathway gene expression with insulin indices in adipose tissues of non-diabetic female adults: a cross-sectional studySemantic proximity Read ↗

A common variation of the PTEN gene is associated with peripheral insulin resistance.Semantic proximity Read ↗

Association of genetic variations in phosphatase and tensin homolog (PTEN) gene with polycystic ovary syndrome in South Indian women: a case control study.Semantic proximity Read ↗

Associations of the PTEN -9C>G polymorphism with insulin sensitivity and central obesity in Chinese.Semantic proximity Read ↗

The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling.Semantic proximity Read ↗

PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase.Semantic proximity Read ↗

Association of promoter methylation and 32-bp deletion of the PTEN gene with susceptibility to metabolic syndrome.Semantic proximity Read ↗

Di-n-butyl phthalate regulates insulin sensitivity in human skeletal muscle cell line through the PI3K-AKT-GLUT4 signaling pathwaySemantic proximity Read ↗

Antisense oligonucleotides against the lipid phosphatase SHIP2 improve muscle insulin sensitivity in a dietary rat model of the metabolic syndrome.Semantic proximity Read ↗

A limited role for PI(3,4,5)P3 regulation in controlling skeletal muscle mass in response to resistance exercise.Semantic proximity Read ↗

Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels.Semantic proximity Read ↗

Hepatic insulin resistance induced by prenatal alcohol exposure is associated with reduced PTEN and TRB3 acetylation in adult rat offspringSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.