Article
Associations of the PTEN -9C>G polymorphism with insulin sensitivity and central obesity in Chinese.
Gene - 25 Sept 2013
Yang Qiu, Cao Hongyi, Xie Shugui, Tong Yuzhen, Zhu Qibo, Zhang Fang, Lü Qingguo, Yang Yan, Li Daigang, Chen Mei, Yu Changyong, Jin Wei, Yuan Yuquan, Tong Nanwei
Abstract excerpt
BACKGROUND: Phosphatase and tensin homolog on chromosome 10 gene (PTEN) is known as a tumor-suppressor gene. Previous studies demonstrated that PTEN dysfunction affects the function of insulin. However, investigations of PTEN single nucleotide polymorphisms (SNPs) and IR-related disease associations are limited. The aim of the present study was to investigate whether its polymorphism could be involved in the risk...
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