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Association of genetic variations in phosphatase and tensin homolog (PTEN) gene with polycystic ovary syndrome in South Indian women: a case control study.

Archives of gynecology and obstetrics - 1 Oct 2020

Siddamalla Swapna, Govatati Suresh, Venu Veena Kunjumol, Erram Nagendram, Deenadayal Mamata, Shivaji Sisinthy, Bhanoori Manjula

Abstract excerpt

PURPOSE: The purpose of the study was to investigate the association between gene phosphate and tensin homolog (PTEN) single nucleotide polymorphisms (SNPs) and risk of developing polycystic ovary syndrome (PCOS) in South Indian women. PTEN is one of the most important tumor suppressor genes that regulate cell proliferation, migration, and death. It is also involved in the maintenance of genome stability. PCOS is...

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PMID: 32583210
DOI: 10.1007/s00404-020-05658-4

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