Article
Association of promoter methylation and 32-bp deletion of the PTEN gene with susceptibility to metabolic syndrome.
Molecular medicine reports - 1 Jan 2013
Hashemi Mohammad, Rezaei Hamzeh, Eskandari-Nasab Ebrahim, Kaykhaei Mahmoud-Ali, Taheri Mohsen
Abstract excerpt
Metabolic syndrome (MeS), a cluster of several metabolic disorders, is increasingly being recognized as a risk factor for type II diabetes (T2D) and cardiovascular disease. Genetic and epigenetic alteration of the phosphatase and tensin homolog deleted on chromosome ten (PTEN) has been associated with components of MeS. The aim of the present study was to investigate the possible association of a 32-bp deletion...
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