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Article

Glucocorticoid and mineralocorticoid receptor polymorphisms and recurrence of major depressive disorder.

Psychoneuroendocrinology - 1 May 2015

Hardeveld Florian, Spijker Jan, Peyrot Wouter J, de Graaf Ron, Hendriks Sanne M, Nolen Willem A, Penninx Brenda W J H, Beekman Aartjan T F

Abstract excerpt

OBJECTIVE: Previous research found that variants of the glucocorticoid receptor (GR) (9β, ER22/23EK, BclI, TthIIIl, NR3C1-1 and N363S) and mineralocorticoid receptor (MR) gene polymorphism (-2 C/G and I180V) are associated with both glucocorticoid (GC) sensitivity and major depressive disorder (MDD). There are no data which investigated prospectively whether these variants are associated with recurrence of MDD....

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PMID: 25765757
DOI: 10.1016/j.psyneuen.2015.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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