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Article

Estrogen receptor alpha gene variants and major depressive episodes.

Journal of affective disorders - 1 Feb 2012

Ryan Joanne, Scali Jacqueline, Carrière Isabelle, Peres Karine, Rouaud Olivier, Scarabin Pierre-Yves, Ritchie Karen, Ancelin Marie-Laure

Abstract excerpt

BACKGROUND: Despite evidence of estrogen's mood-enhancing effects, the association between estrogen receptor (ER) gene variants and lifetime major depression has been insufficiently studied. METHODS: 3987 community-dwelling women aged 65years and over were recruited in France as part of the Three City Study. Current and past major depressive disorders (MDD) were diagnosed using the Mini-International...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22051074
DOI: 10.1016/j.jad.2011.10.010

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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