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Article

Structure-PPi: a module for the annotation of cancer-related single-nucleotide variants at protein-protein interfaces.

Bioinformatics (Oxford, England) - 15 Jul 2015

Vázquez Miguel, Valencia Alfonso, Pons Tirso

Abstract excerpt

MOTIVATION: The interpretation of cancer-related single-nucleotide variants (SNVs) considering the protein features they affect, such as known functional sites, protein-protein interfaces, or relation with already annotated mutations, might complement the annotation of genetic variants in the analysis of NGS data. Current tools that annotate mutations fall short on several aspects, including the ability to use...

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PMID: 25765346
DOI: 10.1093/bioinformatics/btv142
PMCID: PMC4495296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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