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Article

A homologous mapping method for three-dimensional reconstruction of protein networks reveals disease-associated mutations.

BMC systems biology - 19 Mar 2018

Huang Sing-Han, Lo Yu-Shu, Luo Yong-Chun, Tseng Yu-Yao, Yang Jinn-Moon

Abstract excerpt

BACKGROUND: One of the crucial steps toward understanding the associations among molecular interactions, pathways, and diseases in a cell is to investigate detailed atomic protein-protein interactions (PPIs) in the structural interactome. Despite the availability of large-scale methods for analyzing PPI networks, these methods often focused on PPI networks using genome-scale data and/or known experimental PPIs....

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Identifiers

PMID: 29560828
DOI: 10.1186/s12918-018-0537-2
PMCID: PMC5861491

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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