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Article

The XX Sex Chromosome Complement is Required in Male and Female Mice for Enhancement of Immunity Induced by Exposure to 3,4-Dichloropropionanilide.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Aug 2015

Holásková Ida, Franko Jennifer, Goodman Robert L, Arnold Arthur P, Schafer Rosana

Abstract excerpt

PROBLEM: The chemical propanil enhances antibody responses to a heat-killed Streptococcus pneumoniae (HKSP) vaccine. The enhanced response is dependent on gonads in females, but independent of gonads in males. The sex differences in the immune response may be due to sexual differentiation of the immune system or sex chromosome complement. METHOD OF STUDY: To test the hypothesis that the immune system is sexually...

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Source

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Identifiers

PMID: 25765220
DOI: 10.1111/aji.12378
PMCID: PMC4496308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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