Article
Differential Th1 and Th2 cell responses in male and female BALB/c mice infected with coxsackievirus group B type 3.
Journal of virology - 1 Aug 1994
Huber S A, Pfaeffle B
Abstract excerpt
Male and female BALB/c mice differ dramatically in susceptibility to myocarditis subsequent to coxsackievirus B3 (CVB3) infection. CVB3 infection of male mice results in substantial inflammatory cell infiltration of the myocardium, and virus-immune lymphocytes from these animals give predominantly a Th1 cell phenotypic response, as determined by predominant immunoglobulin G2a isotypic antibody production and...
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