Article
Deficiency in circulating T cells in four core genotypes mice with Sry translocation.
Journal of immunology (Baltimore, Md. : 1950) - 4 Aug 2026
McKernan Kaitlin E, Cephus Jacqueline-Yvonne, Kuehnle Shelby N, Henriquez-Pilier Emely, Dandy Aamina C, Bacharier Tess, Polosukhin Vasiliy V, Cahill Katherine N, Silveyra Patricia, Newcomb Dawn C
Abstract excerpt
Sex differences exist in the immune responses to infections and in the prevalence and severity of autoimmune and allergic diseases. These sex differences may be caused by sex hormones and/or variable inactivation of X chromosome genes. The 4 core genotypes mice allow for distinction between the effects of sex hormones and chromosomes on physiology and disease pathology. In the FCG mouse model, the Sry gene is...
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