Article

Estradiol Mediates Greater Germinal Center Responses to Influenza Vaccination in Female than Male Mice

2023-11-27

Abstract excerpt

Adult females of reproductive ages develop greater antibody responses to inactivated influenza vaccine (IIV) than males. How sex, age, and sex steroid changes impact B cells and durability of IIV-induced immunity and protection over 4-months post-vaccination (mpv) was analyzed. Vaccinated adult females had greater germinal center (GC) B cell and plasmablast frequencies in lymphoid tissues, higher neutralizing anti...

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Literature Corpus work: 9157e2c7-f103-5fbf-aa51-520e092d30f5
DOI: 10.1101/2023.11.27.568847

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