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Article

Statins increase the frequency of circulating CD4+ FOXP3+ regulatory T cells in healthy individuals.

Journal of immunology research - 1 Jan 2015

Rodríguez-Perea Ana Lucía, Montoya Carlos J, Olek Sven, Chougnet Claire A, Velilla Paula A

Abstract excerpt

Statins have been shown to modulate the number and the suppressive function of CD4(+)FOXP3(+) T cells (Treg) in inflammatory conditions. However, it is not well established whether statin could also affect Treg in absence of inflammation. To address this question, eighteen normocholesterolemic ma...

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Source

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Identifiers

PMID: 25759848
DOI: 10.1155/2015/762506
PMCID: PMC4352479

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25759848-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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