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Article

A cis-regulatory mutation in troponin-I of Drosophila reveals the importance of proper stoichiometry of structural proteins during muscle assembly.

Genetics - 1 May 2015

Firdaus Hena, Mohan Jayaram, Naz Sarwat, Arathi Prabhashankar, Ramesh Saraf R, Nongthomba Upendra

Abstract excerpt

Rapid and high wing-beat frequencies achieved during insect flight are powered by the indirect flight muscles, the largest group of muscles present in the thorax. Any anomaly during the assembly and/or structural impairment of the indirect flight muscles gives rise to a flightless phenotype. Multiple mutagenesis screens in Drosophila melanogaster for defective flight behavior have led to the isolation and...

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Identifiers

PMID: 25747460
DOI: 10.1534/genetics.115.175604
PMCID: PMC4423360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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