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Article

Transcriptome analysis of IFM-specific actin and myosin nulls in Drosophila melanogaster unravels lesion-specific expression blueprints across muscle mutations.

Gene - 5 Oct 2017

Madan Aditi, Thimmaiya Divesh, Franco-Cea Ari, Aiyaz Mohammed, Kumar Prabodh, Sparrow John C, Nongthomba Upendra

Abstract excerpt

Muscle contraction is a highly fine-tuned process that requires the precise and timely construction of large protein sub-assemblies to form sarcomeres. Mutations in many genes encoding constituent proteins of this macromolecular machine result in defective functioning of the muscle tissue. However, the pathways underlying muscle degeneration, and manifestation of myopathy phenotypes are not well understood. In...

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PMID: 28739398
DOI: 10.1016/j.gene.2017.07.061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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