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Article

Drosophila melanogaster troponin-T mutations engender three distinct syndromes of myofibrillar abnormalities.

Journal of molecular biology - 5 Dec 1990

Fyrberg E, Fyrberg C C, Beall C, Saville D L

Abstract excerpt

In vertebrates troponin complexes interact co-operatively with tropomyosin dimers to modulate skeletal muscle contraction. In order further to investigate troponin assembly and function in vivo, we are developing molecular genetic approaches. Here we report characterization of the gene that encodes Drosophila tropinin-T and analyses of muscle defects engendered by several mutant alleles. We found that the...

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PMID: 2124273
DOI: 10.1016/0022-2836(90)90390-8

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