Drosophila melanogaster troponin-T mutations engender three distinct syndromes of myofibrillar abnormalities.

doi:10.1016/0022-2836(90)90390-8

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Article

Drosophila melanogaster troponin-T mutations engender three distinct syndromes of myofibrillar abnormalities.

Journal of molecular biology - 5 Dec 1990

Fyrberg E, Fyrberg C C, Beall C, Saville D L

Abstract excerpt

In vertebrates troponin complexes interact co-operatively with tropomyosin dimers to modulate skeletal muscle contraction. In order further to investigate troponin assembly and function in vivo, we are developing molecular genetic approaches. Here we report characterization of the gene that encod...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Drosophila melanogaster
Genomic Library
Molecular Sequence Data
Muscles
Mutation
Phenotype
Troponin
Troponin T

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