Article
Genetic association and gene-smoking interaction study of carotid intima-media thickness at five GWAS-indicated genes: the Bogalusa Heart Study.
Gene - 15 May 2015
Li Changwei, Chen Wei, Jiang Fan, Simino Jeannette, Srinivasan Sathanur R, Berenson Gerald S, Mei Hao
Abstract excerpt
OBJECTIVES: To examine the associations of five GWAS-identified genes with carotid intima-media thickness (IMT) in a biracial sample from the Bogalusa Heart Study, and evaluate their participation in gene-smoking interactions. METHODS: Far wall IMTs of common carotid arteries were measured using high-resolution B-mode ultrasound. Both the gene-smoking interactions and single-marker associations were evaluated by...
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