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Article

Genetic architecture of carotid artery intima-media thickness in Mexican Americans.

Circulation. Cardiovascular genetics - 1 Apr 2013

Melton Phillip E, Carless Melanie A, Curran Joanne E, Dyer Thomas D, Göring Harald H H, Kent Jack W, Drigalenko Eugene, Johnson Matthew P, Maccluer Jean W, Moses Eric K, Comuzzie Anthony G, Mahaney Michael C, O'Leary Daniel H, Blangero John, Almasy Laura

Abstract excerpt

BACKGROUND- Intima-media thickness (IMT) of the common and internal carotid arteries is an established surrogate for atherosclerosis and predicts risk of stroke and myocardial infarction. Often IMT is measured as the average of these 2 arteries; yet, they are believed to result from separate biological mechanisms. The aim of this study was to conduct a family-based genome-wide association study (GWAS) for IMT to...

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Identifiers

PMID: 23487405
DOI: 10.1161/CIRCGENETICS.113.000079
PMCID: PMC3865281

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PAX1

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