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Article

Integrative Observational and Genetic Evidence From the UK Biobank Supports Carotid Intima-Media Thickness as a Window Into Cardiac Remodeling.

Journal of the American Heart Association - 7 Jul 2026

Chong Si Hui, Saccoh Adama Fatima, van Vugt Marion, Schmidt Amand Floriaan, Paliwal Nikhil

Abstract excerpt

BACKGROUND: Carotid intima-media thickness (cIMT) is a noninvasive marker of subclinical atherosclerosis linked to future cardiovascular disease (CVD). However, its relationship with early cardiac remodeling and shared genetic basis with cardiovascular disease remain poorly understood. We investigated the phenotypic and genetic associations between cIMT, aortic and cardiac traits, and cardiovascular disease in...

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Source

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Identifiers

PMID: 42396779
DOI: 10.1161/JAHA.125.049139
PMCID: PMC13477355

Genes

CDH13
FBN1
FBXO32
HAND2
ITCH
TBX20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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