Article
Interaction of G-protein beta3 subunit and nitric oxide synthase gene polymorphisms on carotid artery intima-media thickness in young adults: the Bogalusa Heart Study.
American journal of hypertension - 1 Aug 2008
Bhuiyan Azad R, Chen Wei, Srinivasan Sathanur R, Rice Janet C, Mock Nancy B, Tang Rong, Gene Bond M, Boerwinkle Eric, Berenson Gerald S
Abstract excerpt
BACKGROUND: G-protein beta3 subunit (GNB3) gene C825T and endothelial nitric oxide (eNOS) gene G894T polymorphisms both influence arterial structure and function. However, information is scant regarding the interaction of these genes on arterial wall thickness. METHODS: This aspect was examined in 654 white and black subjects, aged 25-43 years (72.9% white, 39.3% male). Arterial wall thickness was assessed in...
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