Article
Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort.
Atherosclerosis - 1 Nov 2015
Xie Gaoqiang, Myint Phyo Kyaw, Voora Deepak, Laskowitz Daniel T, Shi Ping, Ren Fuxiu, Wang Hao, Yang Ying, Huo Yong, Gao Wei, Wu Yangfeng
Abstract excerpt
BACKGROUND: Carotid artery intima media thickness (IMT) in human is a marker of subclinical atherosclerosis with high heritability. Many genome-wide association studies (GWAS) were performed in European and American populations, yet discovery efforts have been limited in Asians. OBJECTIVE: To identify the genetic determinants of 10-year progression of IMT using GWA approach in a Chinese cohort. METHODS:...
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