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Article

Diagnostic value of immunohistochemistry for the detection of the BRAF V600E mutation in colorectal carcinoma.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Ioannou Maria, Papamichali Roidoula, Samara Maria, Paraskeva Efrosini, Papacharalambous Constantina, Baxevanidou Korina, Koukoulis George

Abstract excerpt

PURPOSE: V600E is the most common activating BRAF mutation in colorectal carcinomas (CRCs). It is a crucial biomarker for patient selection and response to targeted therapy with BRAF V600E inhibitors. Previous studies using immunohistochemistry (IHC) have shown different results. In this study, we evaluated the IHC expression of the mutated BRAF protein in archival material from CRC specimens and correlated it...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 27569082

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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