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Article

Transmitted/Founder Viruses Rapidly Escape from CD8+ T Cell Responses in Acute Hepatitis C Virus Infection.

Journal of virology - 1 May 2015

Bull Rowena A, Leung Preston, Gaudieri Silvana, Deshpande Pooja, Cameron Barbara, Walker Melanie, Chopra Abha, Lloyd Andrew R, Luciani Fabio

Abstract excerpt

UNLABELLED: The interaction between hepatitis C virus (HCV) and cellular immune responses during very early infection is critical for disease outcome. To date, the impact of antigen-specific cellular immune responses on the evolution of the viral population establishing infection and on potential escape has not been studied. Understanding these early host-virus dynamics is important for the development of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Epitopes, T-Lymphocyte

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Share to Viral Hepatitis Vaccines

Source

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Identifiers

PMID: 25740982
DOI: 10.1128/JVI.03717-14
PMCID: PMC4442533

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