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Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus andHost

27 Oct 2006

Abstract excerpt

The virological and cellular consequences of persistent hepatitis C virus (HCV) infection have been elusive due to the absence of the requisite experimental systems. Here, we report the establishment and the characteristics of persistent in vitro infection of human hepatoma-derived cells by a recently described HCV genotype 2a infectious molecular clone. Persistent in vitro infection was characterized by the...

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PMID: 16956932
DOI: 10.1128/jvi.01307-06

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