Article
Viral sequence evolution in acute hepatitis C virus infection.
Journal of virology - 1 Nov 2007
Kuntzen Thomas, Timm Joerg, Berical Andrew, Lewis-Ximenez Lia L, Jones Andrea, Nolan Brian, Schulze zur Wiesch Julian, Li Bin, Schneidewind Arne, Kim Arthur Y, Chung Raymond T, Lauer Georg M, Allen Todd M
Abstract excerpt
CD8(+)-T-cell responses play an important role in the containment and clearance of hepatitis C virus (HCV) infection, and an association between viral persistence and development of viral escape mutations has been postulated. While escape from CD8+ -T-cell responses has been identified as a major...
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