Article
Hepatitis C virus--T-cell responses and viral escape mutations.
European journal of immunology - 1 Jan 2012
Petrovic Danijela, Dempsey Eugene, Doherty Derek G, Kelleher Dermot, Long Aideen
Abstract excerpt
Hepatitis C virus (HCV) is a small, enveloped RNA virus and the number of HCV-infected individuals worldwide is estimated to be approximately 170 million. Most HCV infections persist, with up to 80% of all cases leading to chronic hepatitis associated with liver fibrosis, cirrhosis, and hepatocellular carcinoma. HCV-host interactions have a crucial role in viral survival, persistence, pathogenicity of infection,...
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