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Article

Single-cell transcriptogenomics reveals transcriptional exclusion of ENU-mutated alleles.

Mutation research - 1 Feb 2015

Li Wenge, Calder R Brent, Mar Jessica C, Vijg Jan

Abstract excerpt

Recently, great progress has been made in single cell genomics and transcriptomics. Here, we present an integrative method, termed single-cell transcriptogenomics (SCTG), in which whole exome sequencing and RNA-seq is performed concurrently on single cells. This methodology enables one to track germline and somatic variants directly from the genome to the transcriptome in individual cells. Mouse embryonic...

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Identifiers

PMID: 25733965
DOI: 10.1016/j.mrfmmm.2015.01.002
PMCID: PMC4342853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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