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Article

Single cell genomics: advances and future perspectives.

PLoS genetics - 1 Jan 2014

Macaulay Iain C, Voet Thierry

Abstract excerpt

Advances in whole-genome and whole-transcriptome amplification have permitted the sequencing of the minute amounts of DNA and RNA present in a single cell, offering a window into the extent and nature of genomic and transcriptomic heterogeneity which occurs in both normal development and disease. Single-cell approaches stand poised to revolutionise our capacity to understand the scale of genomic, epigenomic, and...

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Identifiers

PMID: 24497842
DOI: 10.1371/journal.pgen.1004126
PMCID: PMC3907301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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