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Article

Mutagenesis of triad determinants of rat Alox15 alters the specificity of fatty acid and phospholipid oxygenation.

Archives of biochemistry and biophysics - 1 Apr 2015

Pekárová Mária, Kuhn Hartmut, Bezáková Lýdia, Ufer Christoph, Heydeck Dagmar

Abstract excerpt

Among lipoxygenases ALOX15 orthologs are somewhat peculiar because of their capability of oxygenating polyenoic fatty acids even if they are incorporated in complex lipid-protein assemblies. ALOX15 orthologs of different species have been characterized before, but little is known about the corresponding rat enzyme. Since rats are frequently employed as models in biomedical research we expressed rat Alox15 as...

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Identifiers

PMID: 25731857
DOI: 10.1016/j.abb.2015.02.029

Genes

ALOX15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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