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Article

Blood pressure interacts with APOE ε4 to predict memory performance in a midlife sample.

Neuropsychology - 1 Sept 2015

Oberlin Lauren E, Manuck Stephen B, Gianaros Peter J, Ferrell Robert E, Muldoon Matthew F, Jennings J Richard, Flory Janine D, Erickson Kirk I

Abstract excerpt

OBJECTIVE: Elevated blood pressure and the Apolipoprotein ε4 allele (APOE ε4) are independent risk factors for Alzheimer's disease. We sought to determine whether the combined presence of the APOE ε4 allele and elevated blood pressure is associated with lower cognitive performance in cognitively healthy middle-aged adults. METHODS: A total of 975 participants aged 30-54 (mean age = 44.47) were genotyped for APOE....

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Source

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Identifiers

PMID: 25730733
DOI: 10.1037/neu0000177
PMCID: PMC4549217

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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