Article
Impact of hypertension and apolipoprotein E4 on poststroke cognition in subjects >75 years of age.
Stroke - 1 Sept 2005
Rowan E, Morris C M, Stephens S, Ballard C, Dickinson H, Rao H, Saxby B K, McLaren A T, Kalaria R N, Kenny R A
Abstract excerpt
BACKGROUND AND PURPOSE: The apolipoprotein E4 allele (APOE4) associates with increased dementia risk, and hypertension may associate with mild cognitive deficits. We examined whether nondemented stroke patients with (1) a prestroke history of hypertension and (2) APOE4 were more cognitively impaired at 3 months after stroke. METHODS: A total of 257 participants were genotyped and outcomes from neuropsychological...
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