Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins.

Neurology - 1 Jun 1998

Carmelli D, Swan G E, Reed T, Miller B, Wolf P A, Jarvik G P, Schellenberg G D

Abstract excerpt

OBJECTIVE: To investigate the combined effect of the apolipoprotein E epsilon4 (ApoE*4) allele and midlife cardiovascular risk factors on cognitive decline. METHODS: Data are from the National Heart, Lung, and Blood Institute Twin Study-a longitudinal cardiovascular epidemiologic study of World W...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aging
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Genotype

Share to Heterozygote

Share to Hypertension

Share to Risk Factors

Source

Identifiers

PMID: 9633697
DOI: 10.1212/wnl.50.6.1580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9633697-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins.PMID 9633697Read ↗

APOE genotype modifies the relationship between midlife vascular risk factors and later cognitive decline.Semantic proximity Read ↗

The effect of apolipoprotein E epsilon4 in the relationships of smoking and drinking to cognitive function.Semantic proximity Read ↗

Blood pressure interacts with APOE ε4 to predict memory performance in a midlife sample.Semantic proximity Read ↗

The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study.Semantic proximity Read ↗

APOE genotype and cognitive decline in a middle-aged cohort.Semantic proximity Read ↗

Vascular risk factors and cognitive decline among elderly male twins.Semantic proximity Read ↗

Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease.Semantic proximity Read ↗

Joint effect of the APOE gene and midlife systolic blood pressure on late-life cognitive impairment: the Honolulu-Asia aging study.Semantic proximity Read ↗

Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele.Semantic proximity Read ↗

Substantial effects of apolipoprotein E ε4 on memory decline in very old age: longitudinal findings from a population-based sample.Semantic proximity Read ↗

Longitudinal genetic analysis of executive function in elderly men.Semantic proximity Read ↗

APOE ε4 and the Influence of Sex, Age, Vascular Risk Factors, and Ethnicity on Cognitive Decline.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.