Article
Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins.
Neurology - 1 Jun 1998
Carmelli D, Swan G E, Reed T, Miller B, Wolf P A, Jarvik G P, Schellenberg G D
Abstract excerpt
OBJECTIVE: To investigate the combined effect of the apolipoprotein E epsilon4 (ApoE*4) allele and midlife cardiovascular risk factors on cognitive decline. METHODS: Data are from the National Heart, Lung, and Blood Institute Twin Study-a longitudinal cardiovascular epidemiologic study of World War II male veteran twins currently in its 27th year of follow-up. Subjects were assessed for cardiovascular risk...
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