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Article

Hypertension moderates the effect of APOE on 21-year cognitive trajectories.

Psychology and aging - 1 Jun 2014

de Frias Cindy M, Schaie K Warner, Willis Sherry L

Abstract excerpt

We examined whether hypertension moderated the effects of apolipoprotein ε4 (APOE ε4) on individual differences in level and change in cognitive functions over a 21-year period using data from the Seattle Longitudinal Study (SLS). A total of 563 nondemented adults ages 32 to 74 years in 1984 (M = 51.06, SD = 12.03) were included in the study. Cognitive performance was assessed spanning 7 domains-verbal...

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Source

Identifiers

PMID: 24956008
DOI: 10.1037/a0036828

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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