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Article

Association of blood pressure with cognitive function at midlife: a Mendelian randomization study.

BMC medical genomics - 26 Aug 2020

Sun Daokun, Thomas Emy A, Launer Lenore J, Sidney Stephen, Yaffe Kristine, Fornage Myriam

Abstract excerpt

BACKGROUND: Whether high blood pressure has a causal effect on cognitive function as early as middle age is unclear. We investigated whether high blood pressure (BP) causally impairs cognitive function at midlife using Mendelian Randomization (MR). METHODS: We applied a two-sample MR approach to investigate the causal relationship between BP and midlife cognitive performance measured by the Digit Symbol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32847530
DOI: 10.1186/s12920-020-00769-y
PMCID: PMC7448985

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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