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Article

Associations between functional polymorphisms and response to biological treatment in Danish patients with psoriasis.

The pharmacogenomics journal - 22 May 2018

Loft N D, Skov L, Iversen L, Gniadecki R, Dam T N, Brandslund I, Hoffmann H J, Andersen M R, Dessau R B, Bergmann A C, Andersen N M, Andersen P S, Bank S, Vogel U, Andersen V

Abstract excerpt

Biological agents including anti-tumor necrosis factor (anti-TNF; adalimumab, infliximab, etanercept) and anti-interleukin-12/13 (IL12/23; ustekinumab) are essential for treatment of patients with severe psoriasis. However, a significant proportion of the patients do not respond to a specific treatment. Pharmacogenetics might be a way to predict treatment response. Using a candidate gene approach, 62 mainly...

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Share to Adalimumab
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Interleukin-1beta

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Source

Identifiers

PMID: 28696418
DOI: 10.1038/tpj.2017.31

Genes

TNF
TIRAP
TLR2
TLR5
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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