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Association between TNF-α polymorphisms and responsiveness to TNF-α blockers in ankylosing spondylitis and psoriatic arthritis: a meta-analysis.

Scientific reports - 13 Mar 2026

Lee Young Ho, Song Gwan Gyu

Abstract excerpt

To investigate the association between tumor necrosis factor-alpha (TNF-α) polymorphisms and the responsiveness to anti-TNF-α therapy in patients with ankylosing spondylitis (AS) and psoriatic arthritis (PsA). A comprehensive literature search of the PubMed/Medline, Embase, and Web of Science databases was performed to identify relevant published studies. Meta-analysis was performed to assess the relationship...

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Alleles
Antirheumatic Agents
Arthritis, Psoriatic
TNF gene
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Spondylitis, Ankylosing

Tumor Necrosis Factor-alpha

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Open in PubMed Open full text

Identifiers

PMID: 41826342
DOI: 10.1038/s41598-025-23987-9
PMCID: PMC13009254

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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