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Distinct Genetic Alterations in Colorectal Cancer

25 Jan 2010

Abstract excerpt

BACKGROUND: Colon cancer (CRC) development often includes chromosomal instability (CIN) leading to amplifications and deletions of large DNA segments. Epidemiological, clinical, and cytogenetic studies showed that there are considerable differences between CRC tumors from African Americans (AAs) and Caucasian patients. In this study, we determined genomic copy number aberrations in sporadic CRC tumors from AAs,...

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PMID: 20126641
DOI: 10.1371/journal.pone.0008879

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