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Article

A genome-wide study of cytogenetic changes in colorectal cancer using SNP microarrays: opportunities for future personalized treatment.

PloS one - 1 Jan 2012

Jasmine Farzana, Rahaman Ronald, Dodsworth Charlotte, Roy Shantanu, Paul Rupash, Raza Maruf, Paul-Brutus Rachelle, Kamal Mohammed, Ahsan Habibul, Kibriya Muhammad G

Abstract excerpt

In colorectal cancer (CRC), chromosomal instability (CIN) is typically studied using comparative-genomic hybridization (CGH) arrays. We studied paired (tumor and surrounding healthy) fresh frozen tissue from 86 CRC patients using Illumina's Infinium-based SNP array. This method allowed us to study CIN in CRC, with simultaneous analysis of copy number (CN) and B-allele frequency (BAF)--a representation of allelic...

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Identifiers

PMID: 22363777
DOI: 10.1371/journal.pone.0031968
PMCID: PMC3282791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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