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Article

Chromosome copy number analysis in screening for prognosis-related genomic regions in colorectal carcinoma.

Cancer science - 1 Sept 2008

Kurashina Kentaro, Yamashita Yoshihiro, Ueno Toshihide, Koinuma Koji, Ohashi Jun, Horie Hisanaga, Miyakura Yasuyuki, Hamada Toru, Haruta Hidenori, Hatanaka Hisashi, Soda Manabu, Choi Young Lim, Takada Shuji, Yasuda Yoshikazu, Nagai Hideo, Mano Hiroyuki

Abstract excerpt

Colorectal carcinoma (CRC) remains the major cause of cancer death in humans. Although chromosomal structural anomaly is presumed to play an important role in the carcinogenesis of CRC, chromosomal copy number alterations (CNA) and loss of heterozygosity (LOH) have not yet been analyzed extensively at high resolution in CRC. Here we aim to identify recurrent CNA and LOH in human CRC with the use of single...

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Identifiers

PMID: 18564138
DOI: 10.1111/j.1349-7006.2008.00881.x
PMCID: PMC11158266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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