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Article

Vascular smooth muscle cells are responsible for a prothrombotic phenotype of spontaneously hypertensive rat arteries.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2015

Ait Aissa Karima, Lagrange Jérémy, Mohamadi Amel, Louis Huguette, Houppert Bénédicte, Challande Pascal, Wahl Denis, Lacolley Patrick, Regnault Véronique

Abstract excerpt

OBJECTIVE: The hypothesis that hypertension induces a hypercoagulable state arises from the complications associated with hypertension: stroke and myocardial infarction. Here, we determine whether hypertension causes changes in the thrombin-generating capacity of the vascular wall. APPROACH AND RESULTS: We used spontaneously hypertensive rats (SHR) compared with Wistar rats. The addition of thoracic aortic rings...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25722431
DOI: 10.1161/ATVBAHA.115.305377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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